CHILDREN with LEUKAEMIA
Scientific Conference, 6-10 September 2004
incidence, causal mechanisms and prevention


















Visitor No:
17,359

 

Scientific Poster Presentation Awards for Young Researchers (under 30)

Poster abstracts may be viewed via the posters page. The posters that were
put up were more detailed than most of the submitted abstracts. When more
complete versions are available to us they will be linked from this page.

Six £15,000 prizes were awarded (in alphabetical order) to:


Elizabeth Ainsbury (P3-3)

An investigation into polarisation as a possible metric with regard to human
exposure to ELF magnetic fields from appliances within the home


Elizabeth A Ainsbury, Emma Conein and Denis L Henshaw
H H Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol, BS8 1TL

One of two posters submitted by Elizabeth Ainsbury, this one was chosen because the panel believe that the degree of ellipticity is an important part of any EMF exposure that has not been taken into account in most previous studies. This could well prove to be one of the important confounders in published epidemiological studies.


Donna Hammal (P2-12)

Paternal occupation as a risk factor for leukaemia and Non-Hodgkin
lymphoma in children and young adults.
A study from the North of England.


Donna M Hammal, Mark S Pearce, M Tevfik Dorak, and Louise Parker.
Paediatric and Lifecourse Epidemiology Research Group, School of Clinical Medical Sciences,
University of Newcastle upon Tyne, RVI, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK

This was an interesting study using good data that suggests that further detailed investigation into the role of paternal electromagnetic field exposure, paternal pesticide/herbicide exposure and predominantly rural occupations, in these cancers in children and young adults is required.


Marylin Kwan (P4-8)

Food consumption of children and risk of childhood leukemia

Marilyn L. Kwan1, Gladys Block, Steve Selvin1, Stacy Month and Patricia A. Buffler.
1Division of Public Health Biology and Epidemiology, School of Public Health, University of California, Berkeley

The committee agreed that this new work had very important implications for the prevention of paediatric leukaemia that will surprise many medical doctors. For the first time, good data was shown linking early childhood diet with risk of developing leukaemia up to age 14. Eating bananas and oranges (or drinking orange juice) frequently while under 2 years of age was shown to approximately halve the risk of development leukaemia during childhood. They also presented limited results showing a similar reduced risk with eating some types of vegetables that needs further work and elucidation.


Michelle Morrow (P1-14)

Functional analysis of TEL-AML1 fusion protein in haematopoietic
progenitor cells in vivo and in vitro.


Michelle Morrow, Sarah Horton, Dimitris Kioussis, Hugh J.M. Brady, and Owen Williams
Paul O'Gorman Centre for Childhood Leukaemia, Molecular Haematology and Cancer Biology Unit,
Institute of Child Health, University College London and Gt. Ormond St. Hospital for Children

This was one of three excellent Poster Presentations from the same laboratory. The committee concluded, after some discussion, that this one was the best to date and awarded it a prize. We look forward to seeing further developments from this laboratory and especially from the main authors of the other two excellent posters, Sarah Horton and Jenny Yeung.


Stuart Peirson (P3-16)

Experimental validation of novel and conventional approaches
to quantitative real-time PCR data analysis


Stuart N. Peirson, Jason N. Butler and Russell G. Foster
Department of Visual Neuroscience, Faculty of Medicine, Imperial College London,
Charing Cross Hospital, Fulham Palace Road, London, W6 8RF.

The committee believes that this technique (in various forms) will become widely used around the world and will play an important role in the diagnosis, treatment and ongoing monitoring of cancer patients. This is excellent, practically useful, work that was well presented.


Kevin Urayama (P4-12)

Influence of cytochrome P450 1A1 genetic polymorphisms on the association
between residential exposure to traffic and childhood leukemia


Kevin Y. Urayama1, Peggy Reynolds et al.
1California Department of Health Services, Environmental Health Investigations Branch, Oakland, CA, USA

The committee agreed that this was exactly the sort of work that was required to untangle any meaning from many of the existing epidemiological studies into the possible causes of childhood leukaemia. Susceptibility of sub-groups with specific genetic markers is a vital direction for epidemiological research to take on board in future studies. This was an excellent example.

All Posters

** IMPORTANT: All downloadable documentation available from this page is strictly the property, intellectually and otherwise, of the author, and it is not reproducable without express permission from the aforesaid author. **

Download full poster list (Word - PDF)

Day 1 - Monday 6th September 2004

P1-1

Effects on glucose uptake in leukaemic lymphocytes of high dilution quinones using the hexokinase and glucose oxidase assays.
       - Rebecca Baghurst and Roger Coghill
Download (pdf - 31.1kb) :: Discussion Forum

 

P1-2

Childhood Cancer Epidemiology among Asian Population in Indian subcontinent. A single Institutional study from a Developing country.
       - Chandra, Sagar and Swaminathan
Download (pdf - 29.7kb) :: Discussion Forum

 

P1-3

Time trends of Childhood Acute Lymphoblastic Leukaemia Incidence and survival and relationship to Socio-economic status and Immunophenotype from a developing country
       - Chandra, Sagar and Swaminathan
Download (pdf - 34.8kb) :: Discussion Forum

 

P1-4

An investigation into the effects of high dilution quinones on peripheral blood leukaemic lymphocyte metabolism.
       - Roger Coghill and Rebecca Baghurst
Download (pdf - 47.7kb) :: Discussion Forum

 

P1-5

HFE-C282Y association in childhood ALL: Pointing towards iron?
       - Dorak, Relton, Hammal, Hall and Parker
Download (pdf - 100kb) :: Discussion Forum

 

P1-6

Reporting a congenital leukemia in a newborn
       - Eghbalian, Monsef and Mojarrad
Download (doc - 40.0kb) :: Discussion Forum

 

P1-7

Detecting small area similarities in the epidemiology of childhood acute lymphoblastic leukaemia and type 1 diabetes: a Bayesian approach
       - Richard G Feltbower, Samuel OM Manda et al
Download (pdf - 109kb) :: Discussion Forum

 

P1-8

Population mixing and childhood leukaemia in Yorkshire, UK
       - Richard G. Feltbower, Roger C. Parslow et al
Download (pdf - 69.7kb) :: Discussion Forum

 

P1-9

Establishment of an in vitro model to identify the molecular mechanism of haematopoietic progenitor cell immortalisation by the MLL-ENL oncogene.
       - Sarah Horton, Inusha de Silva et al
Download (pdf - 14.4kb) :: Discussion Forum

 

P1-10

Space-time clustering analyses of childhood cancers supports a common infectious aetiology
       - Richard J.Q. McNally, Osborn B. Eden et al
Download (pdf - 27.8kb) :: Discussion Forum

 

P1-11

Epidemiological evidence for an infectious origin for childhood leukaemia
       - Richard J.Q. McNally, Osborn B. Eden et al
Download (pdf - 25.6kb) :: Discussion Forum

 

P1-12

Incidence of leukemias in children from El Salvador and Mexico City between 1996 and 2000.
       - Mejía-Aranguré, Bonilla et al
Download (pdf - 90.9kb) :: Discussion Forum

 

P1-13

Risk factors of leukemia in children
       - Alireza Monsef and Fateme Eghbalian
Download (pdf - 12.9kb) :: Discussion Forum

 

P1-14

Functional analysis of TEL-AML1 fusion protein in haematopoietic progenitor cells in vivo and in vitro.
       - Michelle Morrow, Sarah Horton et al
Download (pdf - 14.9kb) :: Discussion Forum

 

P1-15

Searching for causes: focusing epidemiology
       - M J O'Carroll
Download (pdf - 101kb) :: Discussion Forum

 

P1-16

Folate Metabolic Pathway and Susceptibility to Childhood Acute Lymphoblastic Leukaemia in North Portugal. The role of C677T and A1298C MTHFR Polymorphisms.
       - Elisabete Oliveira, Sandra Alves et al
Download (pdf - 56.7kb) :: Discussion Forum

 

P1-17

Rereading the Infective Hypothesis for Childhood Leukaemia
       - Sue R. Roff
Download (pdf - 74.2kb) :: Discussion Forum

 

P1-18

Preliminary Characterization of a New Type of Viruses Isolated from Paediatric Neuroblastoma and Non-Hodgkin's Lymphoma: potential Implications for Aetiology.
       - Ugo Rovigatti, Albert Tam et al
Download (pdf - 228kb) :: Discussion Forum

 

P1-19

Trends in the proportion of childhood leukaemia patients who are 'cured'
       - Anjali Shah
Download (pdf - 40.0kb) :: Discussion Forum

 

P1-20

Dual Targeting of Bruton's Tyrosine Kinase and Janus Kinase 3 With Rationally Designed Inhibitors Prevents Graft-Versus-Host Disease (GVHD)
       - Fatih M. Uckun and Marina Cetkovic-Cvrlje
Download (pdf - 109kb) :: Discussion Forum

 

P1-21

Identification of E2A-HLF candidate target genes and their contribution to leukaemogenesis.
       - Jenny Yeung and Hugh J.M. Brady
Download (pdf - 11.6kb) :: Discussion Forum

 

P1-22

The descriptive epidemiology of childhood leukaemia and childhood brain tumours - a comparison.
       - Patricia McKinney
Download (pdf - 48.3kb) :: Discussion Forum

 

P1-23

Incidence and Survival of Childhood Cancers in Singapore, 1968-1997: a population - based study.
       - Song Yushan and Chia Kee Seng
Download (pdf - 58.0kb) :: Discussion Forum

 

P1-24

Hypertriglyceridaemia, increased truncal adiposity and decreased lean body mass in Prepubertal Leukaemia Survivors after Bone Marrow Transplantation
       - M. Yeap, F. Ryan et al
Download (pdf - 47.7kb) :: Discussion Forum

Day 2 - Tuesday 7th September 2004

P2-1

Radiation-related excess risk of leukemia may be attributable to a small number of people who carry clonally expanded preleukemic cells
       - Nori Nakamura
Discussion Forum

 

P2-2

Aberrant DNA methylation and synthesis in radiation-induced genetic instability and radiation leukaemogenesis
       - Mark Plumb
Download (pdf - 66.5kb) :: Discussion Forum

 

P2-3

Geographical variations of naturally occurring 210Pb supported 210Po in teeth of juveniles in the UK
       - Janet E Allen, Patrick R James et al
Download (pdf - 105kb) :: Discussion Forum

 

P2-4

Childhood Leukaemia Incidence and Background Ionising Radiation - a French ecological study
       - Anne-Sophie Evrard, Denis Hémon et al
Download (pdf - 158kb) :: Discussion Forum

 

P2-5

Childhood leukemia and lymphoma in Ukraine in post-Chernobyl period: morphocytochemical and immunophenotypic aspects
       - Daniil F. Gluzman, Lilia M. Sklyarenko et al
Download (pdf - 79.0kb) :: Discussion Forum

 

P2-6

Acute myeloid leukemia: Incidence and observed survival in children of Belarus
       - Natallia N. Savva, Olga V. Aleinikova et al
Download (pdf - 91.9kb) :: Discussion Forum

 

P2-7

Does nuclear pollution cause childhood luekaemia? Evidence from the Menai Strait, North Wales
       - Busby C, Bramhall Ret al
Download (pdf - 112kb) :: Discussion Forum

 

P2-8

Infant leukaemia after Chernobyl: the environment ionising radiation hypothesis revisited
       - Chris Busby, Molly Scott Cato et al
Download (pdf - 100kb) :: Discussion Forum

 

P2-9

Childhood acute leukemia, polymorphisms of metabolism enzyme genes and interactions with maternal smoking during pregnancy
       - Stephanie Bellec, Marie-Anne Loriot et al
Download (pdf - 112kb) :: Discussion Forum

 

P2-10

Association of RAS mutation, hyperdiploidy, and parental characteristics with childhood acute leukemia
       - Jeffrey Chang, Yan Zhang et al
Download (pdf - 126kb) :: Discussion Forum

 

P2-11

Parental smoking and the risk of childhood leukaemia
       - Jeffrey S Chang, Patricia A Buffler et al
Download (pdf - 120kb) :: Discussion Forum

 

P2-12

Paternal occupation as a risk factor for leukaemia and Non-Hodgkin lymphoma in children and young adults. A study from the North of England.
       - Donna M Hammal, Mark S Pearce et al
Download (pdf - 93.1kb) :: Discussion Forum

 

P2-13

Use of medication during pregnancy and risk of childhood leukemia
       - Amanda K. Shaw, Claire Infante-Rivard et al
Download (pdf - 116kb) :: Discussion Forum

 

P2-14

Cosmic-ray Induced Aerosol Particle Charging, Implications for Exposure to Children and Pregnant Women in Aircraft
       - R.J. Wilding and R.G. Harrison
Download (pdf - 89.7kb) :: Discussion Forum

Day 3 - Wednesday 8th September 2004

P3-1

Transmission-Line Electric Field Induction in Humans as Influenced by Corona Space Charge
       - Mazen Abdel-Salam and Doaa Mazen
Download (pdf - 26.5kb) :: Discussion Forum

 

P3-2

Polarisation of 50 Hz magnetic fields from the UK power distribution network, in relation to childhood leukaemia and other illnesses
       - Ainsbury E.A., Conein E. and Henshaw D.L.
Download (pdf - 86.4kb) :: Discussion Forum

 

P3-3

An investigation into polarisation as a possible metric with regard to human exposure to ELF magnetic fields from appliances within the home
       - Ainsbury E.A., Conein E. and Henshaw D.L.
Download (pdf - 34.0kb) :: Discussion Forum

 

P3-4

Determination of melatonin in edible plants and medicinal herbs: Comparison of different methods, including UV spectroscopy and GC/MS, with reference to its application in immunodegenerative disorders.
       - Rebecca Baghurst and Chris Busby
Download (pdf - 95.6kb) :: Discussion Forum

 

P3-5

Melatonin, ionizing radiation and damage to the haemopoeitic system
       - D. Bowler, D. Macdonald et al
Download (pdf - 22.5kb) :: Discussion Forum

 

P3-6

Investigation into the responsive emission of melatonin from lymphocytes challenged by the mitogen PHA: is this compromised by exposure to ELF EM Fields?
       - Roger Coghill
Download (pdf - 33.6kb) :: Discussion Forum

 

P3-7

ELF electric fields: the missing metric in childhood leukaemia epidemiology?
       - Roger Coghill
Download (pdf - 35.3kb) :: Discussion Forum

 

P3-8

Quantum-mechanical interference and the biological effects of weak alternating magnetic fields: an assessment of a recent model
       - J. Colin Gill
Download (pdf - 158kb) :: Discussion Forum

 

P3-9

Graham/Stetzer Filters Improve Power Quality in Homes and Schools, Reduce Blood Sugar Levels in Diabetics, Multiple Sclerosis Symptoms, and Headaches.
       - Magda Havas and David Stetzer
Download (pdf - 83.1kb) :: Discussion Forum

 

P3-10

Do magnetic fields cause increased risk of childhood leukaemia via melatonin disruption?
       - Denis L Henshaw and Russel J Reiter
Download (pdf - 41.2kb) :: Discussion Forum

 

P3-11

A Japanese study on childhood leukemia in relation to residential background exposure to extremely-low-frequency electromagnetic fields
       - Michinori Kabuto, Yasushi Honda et al
Download (pdf - 126kb) :: Discussion Forum

 

P3-12

Relation between electromagnetic fields and acute leukemia in children with Down syndrome
       - Mejia-Arangure, Perez-Saldivar et al
Download (pdf - 81.8kb) :: Discussion Forum

 

P3-13

A Japanese study on childhood leukemia in relation to the use of electric appliances
       - Tomohiro Saito, Michinori Kabuto et al
Download (pdf - 51.2kb) :: Discussion Forum

 

P3-14

Assessment of the spatial distribution of cancers with respect to high voltage powerlines: a novel GIS and finite element approach.
       - MG Wright, MB Smith et al
Download (pdf - 79.0kb) :: Discussion Forum

 

P3-15

The Quantum Coherent Organism & EMF Sensitivity
       - Mae-Wan Ho
Download (pdf - 20.0kb) :: Discussion Forum

 

P3-16

Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis
       - Stuart Peirson, J. Butler and R. Foster
Download (pdf - 14.7kb) :: Discussion Forum

Day 4 - Thursday 9th September 2004

P4-1

Effect of high dilution quinones on O2 uptake by peripheral blood lymphocytes: a polarigraphic study
       - Christopher M A Conners and Roger W Coghill
Download (pdf - 50.0kb) :: Discussion Forum

 

P4-2

Childhood leukaemia and road traffic: second step of a case-control study
       - Paolo Crosignani, Rosaria Fissi et al
Download (pdf - 62.2kb) :: Discussion Forum

 

P4-3

Electrical charging of nano-sized airborne pollutants
       - A. Peter Fews, Paul A. Keitch et al
Download (pdf - 112kb) :: Discussion Forum

 

P4-4

Corona ion emissions from high voltage powerlines and implications for human health
       - A. Peter Fews, Paul A. Keitch et al
Download (pdf - 134kb) :: Discussion Forum

 

P4-5

MTHFR polymorphisms, Maternal Folate Intake, and Childhood Leukemia
       - Neela Guha, Joseph Wiemels et al
Download (pdf - 149kb) :: Discussion Forum

 

P4-6

Twentieth century air pollution near London: a reconstruction from measurements of atmospheric electricity
       - R. Giles Harrison
Download (pdf - 58.8kb) :: Discussion Forum

 

P4-7

The effect of electric charge on deposition of environmental aerosols in a mechanical model lung
       - Keitch P.A., Fews A.P., Henshaw D.L.
Download (pdf - 161kb) :: Discussion Forum

 

P4-8

Food consumption of children and risk of childhood leukemia
       - Marilyn L. Kwan, Gladys Block et al
Download (pdf - 178kb) :: Discussion Forum

 

P4-9

Non-occupational exposure to pesticides and childhood acute leukaemia
       - Florence Menegaux and Jacqueline Clavel
Download (pdf - 87.7kb) :: Discussion Forum

 

P4-10

Critical windows of exposure to household pesticides and childhood leukemia: follow-up from the Northern California Childhood Leukemia Study
       - Catherine Metayer, Patricia A Buffler et al
Download (pdf - 82.4kb) :: Discussion Forum

 

P4-11

The role of dietary turmeric for the low incidence of childhood leukemia in Asian Countries
       - Nagabhushan, Kolpe and Ramaswamy
Download (pdf - 82.6kb) :: Discussion Forum

 

P4-12

Influence of cytochrome P450 1A1 genetic polymorphisms on the association between residential exposure to traffic and childhood leukemia
       - Kevin Y. Urayama, Peggy Reynolds et al
Download (pdf - 180kb) :: Discussion Forum

 

P4-13

Frequency - a Unifying Parameter in Leukaemia Studies
       - Cyril W Smith
Download (pdf - 78.6kb) :: Discussion Forum

Day 5 - Friday 10th September 2004

P5-1

The new California Department of Education EMF policy regarding schools, transmission lines and EMF
       - Cindy L Sage, S. Amy Sage
Download (pdf - 18.8kb) :: Discussion Forum

 

P5-2

Epidemiology for decisionmakers: A visual guide to residential and occupational EMF epidemiological results on leukemia 1979-2002
       - Cindy L Sage, S. Amy Sage
Download (pdf - 11.5kb) :: Discussion Forum